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XLH ResearchPeter Rowe is an Associate Professor at the University of Texas. He recently proposed an integrated model linking together the different key actors of the XLH condition : PHEX (the mutated protein of XLH patients), MEPE, FGF23. On his website, he presents a remarkable animated model explaining the biochemical events leading to the symptoms observed in XLH. To my knowledge, this is the more integrated biochemical model explaining our condition. Please click on the following link for animation:MEPE-ASARM model. Copyright (C) 2005 by Pol Harvengt. |
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